DHEA-S

What is Dehydroepiandrosterone Sulfate (DHEA-S)?

Dehydroepiandrosterone Sulfate (DHEA-S) is a hormone primarily produced in the adrenal glands. It plays an important role in the production of androgens and estrogens, the male and female sex hormones. DHEA-S is a sulfated derivative of DHEA and serves as a reservoir that can be converted into active hormones as needed.

Why should you have DHEA-S tested?

Testing DHEA-S can be useful for individuals experiencing symptoms that might indicate hormonal imbalances, such as fatigue, decreased libido, and changes in body composition. It may also be recommended for people who have an underlying condition that affects hormone production, such as adrenal insufficiency or polycystic ovary syndrome (PCOS).

What does it indicate?

DHEA-S levels can provide insight into overall hormonal health. Abnormal levels may point to various health issues, including adrenal dysfunction, potential adrenal cancer or tumors, and hormonal imbalances that may contribute to fertility problems.

What does a high DHEA-S level mean?

A high level of DHEA-S may indicate an overproduction of androgens, leading to symptoms such as acne, excessive hair growth in women (hirsutism), and other signs of masculinization. It may also be an indication of adrenal hyperplasia or adrenal neoplasms.

What does a low DHEA-S level mean?

A low level of DHEA-S may indicate reduced adrenal function, which can lead to symptoms such as fatigue, muscle weakness, and decreased immunity. It may also point to more serious conditions like Addison's disease.