Iron Status (Ferritin + Transferrin Saturation)

What is Iron Status: Ferritin and Transferrin Saturation?

Iron status is determined by two important biomarkers: Ferritin and Transferrin Saturation (TRAFS). Ferritin indicates the amount of stored iron in your body, while Transferrin Saturation indicates how much of the iron transport protein transferrin is saturated with iron. Together, these two values provide a complete insight into both your iron reserves and the transport of iron in your blood.

Why should you test Iron Status: Ferritin and Transferrin Saturation?

This test provides the most accurate picture of your iron status. It is useful for distinguishing between different causes of iron deficiency and for detecting iron overload. The combination is particularly important when experiencing symptoms of fatigue, or when conditions such as hemochromatosis or chronic inflammation are suspected.

What does it indicate?

The combination of Ferritin and Transferrin Saturation helps in diagnosing various iron disorders. A low ferritin level with low transferrin saturation suggests true iron deficiency, while a normal ferritin level with low transferrin saturation may indicate functional iron deficiency due to inflammation.

What does a high level of Ferritin and Transferrin Saturation mean?

High levels of both parameters may indicate iron overload, such as in hereditary hemochromatosis. This can lead to iron accumulation in organs such as the liver, heart, and pancreas, which can be harmful in the long term.

What does a low level of Ferritin and Transferrin Saturation mean?

Low levels of both parameters indicate iron deficiency anemia. Your body has insufficient iron stores and also cannot transport enough iron to the tissues where it is needed. This can lead to fatigue, concentration problems, and other symptoms of iron deficiency.

Ferritin + Transferrin Saturation (TRAFS)