Blood collection at collection point
- You receive a test kit with tubes and referral letter
- Visit one of 800+ collection locations in the Netherlands
- Experienced staff professionally draw your blood
- Receive your results digitally by email
Active Vitamin B12 (Holo-TC)
Holo‑TC; sensitive B12 marker.
€55.00EUR
€20.00EUR
€5.95EUR
Costs are per order
- TrustPilot 4.6/5 sterren
- No GP referral needed
- Reviewed by BIG-registered physician
- ISO 15189 Certified laboratory
- Results within 1 week
- Order today, ships today
What is HOLO-TC?
Holotranscobalamin (HOLO-TC) is a biomarker that measures the amount of vitamin B12 in the body that is directly available for cellular uptake. It is an early indicator of vitamin B12 deficiency, as it only reflects the portion of vitamin B12 that can be actively used by the body.
Why should you have HOLO-TC tested?
Testing HOLO-TC is useful for people experiencing symptoms that may indicate a vitamin B12 deficiency, such as fatigue, weakness, memory problems, or neurological changes. It is also valuable for individuals at risk of vitamin B12 deficiency, such as the elderly, vegans, and people with certain stomach conditions or who use specific medications.
What does it indicate?
HOLO-TC levels indicate the amount of immediately available vitamin B12 in the blood. This helps determine whether the body has sufficient vitamin B12 for essential functions such as DNA synthesis, blood cell production, and nerve maintenance.
What does a high HOLO-TC level mean?
A high level of HOLO-TC is generally uncommon and is less frequently associated with health problems. However, in rare cases, it can indicate certain medical conditions or the use of vitamin B12 supplements.
What does a low HOLO-TC level mean?
A low level of HOLO-TC indicates a deficiency of available vitamin B12 in the body. This can lead to various health problems, including anemia, nerve damage, fatigue, and cognitive impairments.
