Androstenedione

What is Androstenedione?

Androstenedione is a precursor steroid hormone produced in the adrenal glands, testes, and ovaries. It plays a crucial role in the biosynthesis of the male and female sex hormones, testosterone and estrogen. The concentration of androstenedione in the blood can provide insight into the hormonal status and the function of the endocrine glands.

Why should you have Androstenedione tested?

Testing for androstenedione can be useful for assessing hormonal balance and the function of sex hormones. It can aid in the evaluation of conditions such as congenital adrenal hyperplasia (CAH), polycystic ovary syndrome (PCOS), and other conditions related to an excess or deficiency of androgens. It can also offer insight into fertility problems and assist in evaluating the cause of irregular menstrual cycles, excessive hair growth, or acne.

What does it indicate?

The amount of androstenedione in the blood provides insight into the body's production of androgens. The level of this hormone can indicate the activity of the adrenal glands and the gonads (testes or ovaries) and can help in the evaluation of hormonal imbalances and related conditions.

What does a high Androstenedione level mean?

A high level of androstenedione may indicate increased androgen production, which could point to conditions such as CAH, PCOS, or other hormonal imbalances causing an overproduction of androgens. This can lead to symptoms such as irregular menstruation, acne, and hirsutism in women, and hormonal imbalance in men.

What does a low Androstenedione level mean?

A low level may indicate insufficient production of sex hormones, which could suggest hypogonadism, adrenal insufficiency, or other conditions affecting the endocrine system. It may lead to symptoms such as reduced libido, fatigue, and loss of muscle mass.