ANA; autoimmune serology.
Blood collection at collection point
After your order you receive instructions by email
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Blood collection at 1,000+ locations across the Netherlands
Anti-nuclear antibodies (ANA) are antibodies directed against structures within the cell nucleus and are often found in individuals with certain autoimmune diseases. The ANA screening is a blood test that detects the presence of these antibodies, which may indicate the presence of an autoimmune disease such as lupus, rheumatoid arthritis, or scleroderma.
An ANA screening is recommended when someone exhibits symptoms that may suggest an autoimmune disease, such as joint pain, muscle pain, fever, fatigue, and skin rash. The test assists in diagnosing autoimmune diseases and can be important for planning the appropriate treatment.
The presence of ANA in the blood may indicate an autoimmune disease. It is important to note that some people may test positive for ANA without having an autoimmune disease. Therefore, ANA test results are always interpreted in the context of an individual's symptoms and other diagnostic tests.
A positive ANA test indicates the presence of antibodies against cell nuclear components. This may suggest an autoimmune disease, but it is not specific to one disease. Further tests are often required to identify the specific condition.
A negative ANA test means that no ANA was detected in the blood. This may suggest that the likelihood of certain autoimmune diseases is lower, but it does not completely rule out the possibility. Other factors and tests may be necessary for a full evaluation.
Answers to what people usually want to know.
After ordering we generate a referral letter and email you the instructions. You pick a collection point yourself and book an appointment there. Blood is drawn at the location, processed at the lab, and your result arrives digitally.
Often within a few working days. How soon you can be seen depends on how busy the location is and the type of analysis. For specialist analyses we first ship collection materials, which takes a bit longer.
At most collection points yes. Some accept walk-ins. This is clearly indicated per location. You choose the location that works best for you.
That depends on the test. Whether fasting is required, and from what time, is clearly stated in the instructions you receive after ordering. No surprises at the counter.
It varies per analysis: from same-day to a few working days. Standard values often come back quickly; analyses that go to an external lab can take a bit longer. You get an email with a link to your digital result, including a short explanation per value.
We work with 1,000+ collection points across the Netherlands. After ordering you'll see which locations near you are available and you pick where you'd like to go.
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Klantenservice was erg behulpzaam in het beantwoorden van mijn vragen. Ik had ook een extra setje buizen nodig als back-up en dat was geen probleem. Ik had een groot test panel besteld, maar de resultaten waren binnen 1 week binnen. Rapport zag er netjes uit.
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This test is included in Dutch healthcare guidelines and is regularly used for its respective indications.
Rationale for this test
ANA-screening is een standaard-bepaling in de Nederlandse diagnostiek van auto-immuunziekten zoals lupus en andere reumatische aandoeningen. De test is opgenomen in NVKC-richtlijnen en wordt breed toegepast in de reguliere zorg. De klinische betekenis is goed onderbouwd, met hoge sensitiviteit voor systemische lupus erythematodes (SLE) en andere bindweefselziekten.
Last reviewed on
Dutch clinical guidelines and healthcare organisations
International scientific literature
We recommend consulting these independent sources before ordering a preventive health check.
Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.
Independent information about preventive health checks from the National Institute for Public Health and the Environment.
Reliable patient information about illnesses and complaints from Dutch GPs (NHG).
Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.