Estradiol (E2)

What is Estradiol (17-β-estradiol)?

Estradiol, also known as 17-beta-estradiol (17 beta estradiol) or E2, is an essential hormone found in both men and women. As the most active form of estrogen, it plays a crucial role in various bodily functions, including hormonal balance, bone health, and reproductive functions. Also known as estradiol, estrogen or oestrogen.

Why should you test Estradiol?

Measuring estradiol levels is important for diagnosing hormonal imbalance and monitoring reproductive health. The test is used for fertility issues, monitoring hormone therapies, and evaluating symptoms that may indicate hormonal disorders.

In women: useful for menstrual cycle problems, fertility issues, menopause symptoms, hormone therapy monitoring, and evaluation of ovarian function.

In men: useful for reduced libido, erectile dysfunction, gynecomastia (breast development), fertility investigation, and hormone therapy monitoring.

What does it indicate?

Estradiol levels provide insight into hormonal balance and may indicate various conditions. Deviations can point to problems with the gonads, tumors, liver disorders, or exposure to external hormones.

What does a high estradiol level mean?

In women: may indicate ovarian tumors, pregnancy, or ovarian hyperstimulation.

In men: may lead to gynecomastia and emotional instability, and may indicate testicular tumors, liver disease, or the effect of certain medications.

What does a low estradiol level mean?

In women: may indicate reduced ovarian function, early menopause, or fertility problems.

In men: may indicate reduced gonadal function, pituitary problems, osteoporosis, or increased risk of bone fractures in older men.

17-beta-estradiol Estradiol (17-β-) (E2) from serum.