Active Vitamin B12 (fingerstick)

Active B12 (holotranscobalamin); sensitive marker for B12 status.

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€55.00EUR

Collection at test locationN/A
Home test kit delivery

€5.95EUR

Costs are per order

  • TrustPilot 4.6/5 sterren
  • No GP referral needed
  • Reviewed by BIG-registered physician
  • ISO 15189 Certified laboratory
  • At-home fingerstick collection
  • Order today, ships today
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Fingerstick at home – no collection point needed

  • You receive a fingerstick kit with clear instructions
  • Easily collect a few drops of blood yourself
  • Return via medical mail to the lab

What is HOLO-TC?

Holotranscobalamin (HOLO-TC) is a biomarker that measures the amount of vitamin B12 in the body that is directly available for cellular uptake. It is an early indicator of vitamin B12 deficiency because it only reflects the portion of vitamin B12 that can be actively used by the body.

Why should you have HOLO-TC tested?

Testing HOLO-TC is useful for people experiencing symptoms that may indicate a vitamin B12 deficiency, such as fatigue, weakness, memory problems, or neurological changes. It is also valuable for individuals at risk of vitamin B12 deficiency, such as the elderly, vegans, and those with certain gastric conditions or who use certain medications.

What does it indicate?

HOLO-TC levels indicate the amount of readily available vitamin B12 in the blood. This helps determine whether the body has sufficient vitamin B12 for essential functions such as DNA synthesis, blood cell production, and nerve maintenance.

What does a high HOLO-TC level mean?

A high level of HOLO-TC is generally uncommon and less frequently associated with health problems. However, in rare cases, it may indicate certain medical conditions or the use of vitamin B12 supplements.

What does a low HOLO-TC level mean?

A low level of HOLO-TC indicates a deficiency of available vitamin B12 in the body. This can lead to various health issues, including anemia, nerve damage, fatigue, and cognitive impairments.