Methylmalonic acid in urine; for suspected B12 deficiency.

Urine test at home – no collection point needed
You receive a urine collection kit with clear instructions
Easily collect a urine sample yourself
Return via medical mail to the lab
Methylmalonic Acid (MMA) is a biomarker found in the urine and can assist in diagnosing Vitamin B12 deficiency. Vitamin B12 is crucial for the function of the nervous system and the production of red blood cells.
An MMA test can be useful if you have symptoms such as fatigue, weakness, constipation, loss of appetite, and tingling in the hands and feet. Testing for MMA is particularly helpful for the early detection of Vitamin B12 deficiency, even before the first symptoms occur.
An elevated level of MMA in the urine often indicates a Vitamin B12 deficiency. This is because Vitamin B12 is required for the breakdown of methylmalonic acid in the body.
A high level of MMA in the urine usually indicates a Vitamin B12 deficiency. This can lead to anemia, nerve damage, and other health issues if left untreated.
A low or normal MMA level in the urine suggests that sufficient Vitamin B12 is present in the body and that a deficiency is unlikely.
This test is included in Dutch healthcare guidelines and is regularly used for its respective indications.
Rationale for this test
Methylmalonzuur (MMA) in urine is een gevestigde biomarker voor vitamine B12-tekort binnen de Nederlandse reguliere geneeskunde. De test wordt beschouwd als de meest gevoelige en specifieke marker voor de vitamine B12-status op cellulair niveau en is opgenomen in de NHG-richtlijnen voor laboratoriumdiagnostiek bij verdenking op B12-deficiëntie. De klinische betekenis is goed onderbouwd.
Dutch clinical guidelines and healthcare organisations
International scientific literature
We recommend consulting these independent sources before ordering a preventive health check.
Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.
Independent information about preventive health checks from the National Institute for Public Health and the Environment.
Reliable patient information about illnesses and complaints from Dutch GPs (NHG).
Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.
Practical information
After ordering we ship the collection kit to your home. You collect urine following the instructions, return it in the envelope, and receive your result digitally by email.
Follow the included instructions, usually the midstream method in a sterile container. Pay attention to the right timing (first morning urine or random, depending on the test).
For some tests yes (e.g. certain foods or supplements). Whether this applies is stated in the instructions. Read them before you start.
Usually 2 to 5 working days after the lab receives your sample. You receive your laboratory report securely by email. It lists the measured values, units, reference ranges and any flags added by the laboratory.
In the included return envelope with free medical shipping. Drop it in the mailbox; the lab processes your sample as soon as it arrives. For some tests it's important to send it the same day — the instructions make this clear.
Feel free to contact us via WhatsApp, email or phone. We're happy to help you before, during or after your test. If the collection doesn't work, we'll arrange a solution or send new materials — no hassle.
This is why clients choose us
“Very positive experience”
From ordering to having my blood drawn, everything went smoothly and was well organised. I really appreciated being able to visit a blood collection location in my own town so quickly. I received clear instructions beforehand, and the results arrived promptly by email too. Very satisfied!
“Good communication”
This company responds to questions thoroughly and promptly. The entire process, from requesting the test to having blood drawn and receiving the results, runs very smoothly. Overall, I am very satisfied!
“Wide choice of tests, fast and affordable”
You can choose the tests yourself. Fast delivery and processing, clear instructions and affordable.
“I am satisfied with the service”
I received a referral by email, just like from a GP. I did not have to send anything by post and could quickly visit a local blood collection centre. The results were fast and clear. The price was good, not too expensive, and all messages were secure.
“A very good experience”
A very good experience! I received quick answers to my questions, a custom blood test was put together, everything was arranged smoothly, and I could have my blood drawn by a healthcare professional nearby. The results were available within a few days. In short, very satisfied!
“Very good customer service”
The customer service is very good. I had a complex request, which caused an issue at the blood collection centre. Customer service resolved it very well. They also offer a wide range of tests at a reasonable price.
“Everything was well organised”
Everything was well organised. The products were delivered within a few days and, after sending in the samples, the results arrived within a few days too. Communication and information throughout the process were clear and friendly.
“Fantastic service”
Fantastic service! Very good customer service that responds quickly and thinks along with you. Good prices. I will definitely use BloedCheckup's services again.
“Very happy to have found this business”
Very happy to have found this business. We need to check our blood more often :) The process was easy. They sent me the kit at home, then I had to go to a clinic with the papers and they knew what they had to do. I got the results in less than a week.
“Smooth process and good support”
Amazing website experience. I ordered various tests for 2 people. We went to one of the supported centers and took samples. Also after the results were ready, I needed a letter from the laboratory and they prepared the letter for me in no time. Definitely recommended.
“Amazing service!”
Received a packet with everything needed, went to a walk in clinic (Amsterdam DC Clinic) where my blood was drawn and I was out the door within 5 minutes, and then after posting the samples, received results 2 days later. Results were easy to understand as well. Amazing service, would highly recommend!
“Great customer service”
I ordered a test through bloedcheckup.nl but later realized I no longer needed it. I contacted their support team, and they were very quick, responsive, and helpful in handling my cancellation. The whole process was smooth and efficient. Great customer service!