SHBG; binding of testosterone and estradiol.

Fingerstick at home – no collection point needed
You receive a fingerstick kit with clear instructions
Easily collect a few drops of blood yourself
Return via medical mail to the lab
SHBG (Sex Hormone-Binding Globulin) is a protein produced in the blood that plays a crucial role in regulating the amount of sex hormones, including testosterone and estrogen, that are available to the body. It binds to these hormones, thereby affecting their activity.
An SHBG test can be useful for assessing various hormonal imbalances. It is especially helpful when there are symptoms suggesting possible issues with sex hormones, such as unexplained fatigue, fertility problems, menstrual irregularities, or symptoms of testosterone levels that are too high or too low.
SHBG levels in the blood can provide insight into the amount of active sex hormones available to the body. This can assist in the diagnosis of conditions related to hormonal imbalance.
A high level of SHBG may indicate a reduced amount of available active sex hormones. This can cause symptoms such as decreased libido, fatigue, and muscle weakness. It may also point to underlying conditions such as hyperthyroidism or liver diseases.
A low level of SHBG suggests that more active sex hormones are available than normal, potentially leading to symptoms such as acne, excessive hair growth, and in some cases, an increased risk of developing hormone-sensitive conditions.
This test is included in Dutch healthcare guidelines and is regularly used for its respective indications.
Rationale for this test
SHBG is een gevestigde laboratoriumtest binnen de Nederlandse reguliere geneeskunde voor het beoordelen van hormonale disbalansen. De test wordt gebruikt bij de diagnostiek van aandoeningen zoals PCOS, vruchtbaarheidsproblemen en symptomen van testosteron- of oestrogeenafwijkingen. De klinische betekenis en interpretatie zijn goed onderbouwd in de klinisch-chemische praktijk.
Dutch clinical guidelines and healthcare organisations
International scientific literature
We recommend consulting these independent sources before ordering a preventive health check.
Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.
Independent information about preventive health checks from the National Institute for Public Health and the Environment.
Reliable patient information about illnesses and complaints from Dutch GPs (NHG).
Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.
Practical information
After ordering we ship the collection kit to your home. You prick your fingertip, collect a few drops of blood, return it in the envelope, and receive your result digitally by email.
A small prick on your fingertip lets you collect a few drops into a tube. The instructions include step-by-step photos and video, so no guessing required.
Usually 2 to 5 working days after the lab receives your sample. You receive your laboratory report securely by email. It lists the measured values, units, reference ranges and any flags added by the laboratory.
Some people find the fingerstick tricky at first. Warm your hands, hang your arm down, and prick the side of the fingertip for better blood flow. If it still doesn't work, get in touch.
In the included return envelope with free medical shipping. Drop it in the mailbox; the lab processes your sample as soon as it arrives. For some tests it's important to send it the same day — the instructions make this clear.
Feel free to contact us via WhatsApp, email or phone. We're happy to help you before, during or after your test. If the collection doesn't work, we'll arrange a solution or send new materials — no hassle.
This is why clients choose us
“Very positive experience”
From ordering to having my blood drawn, everything went smoothly and was well organised. I really appreciated being able to visit a blood collection location in my own town so quickly. I received clear instructions beforehand, and the results arrived promptly by email too. Very satisfied!
“Good communication”
This company responds to questions thoroughly and promptly. The entire process, from requesting the test to having blood drawn and receiving the results, runs very smoothly. Overall, I am very satisfied!
“Wide choice of tests, fast and affordable”
You can choose the tests yourself. Fast delivery and processing, clear instructions and affordable.
“I am satisfied with the service”
I received a referral by email, just like from a GP. I did not have to send anything by post and could quickly visit a local blood collection centre. The results were fast and clear. The price was good, not too expensive, and all messages were secure.
“A very good experience”
A very good experience! I received quick answers to my questions, a custom blood test was put together, everything was arranged smoothly, and I could have my blood drawn by a healthcare professional nearby. The results were available within a few days. In short, very satisfied!
“Very good customer service”
The customer service is very good. I had a complex request, which caused an issue at the blood collection centre. Customer service resolved it very well. They also offer a wide range of tests at a reasonable price.
“Everything was well organised”
Everything was well organised. The products were delivered within a few days and, after sending in the samples, the results arrived within a few days too. Communication and information throughout the process were clear and friendly.
“Fantastic service”
Fantastic service! Very good customer service that responds quickly and thinks along with you. Good prices. I will definitely use BloedCheckup's services again.
“Very happy to have found this business”
Very happy to have found this business. We need to check our blood more often :) The process was easy. They sent me the kit at home, then I had to go to a clinic with the papers and they knew what they had to do. I got the results in less than a week.
“Smooth process and good support”
Amazing website experience. I ordered various tests for 2 people. We went to one of the supported centers and took samples. Also after the results were ready, I needed a letter from the laboratory and they prepared the letter for me in no time. Definitely recommended.
“Amazing service!”
Received a packet with everything needed, went to a walk in clinic (Amsterdam DC Clinic) where my blood was drawn and I was out the door within 5 minutes, and then after posting the samples, received results 2 days later. Results were easy to understand as well. Amazing service, would highly recommend!
“Great customer service”
I ordered a test through bloedcheckup.nl but later realized I no longer needed it. I contacted their support team, and they were very quick, responsive, and helpful in handling my cancellation. The whole process was smooth and efficient. Great customer service!