Distinguishes Closed Gut from Leaky Gut. Analyzes mucosal integrity and gut immunity.
Feces Home Test
Collect a small sample with the spatula
Place the sample in the provided tube
Return via medical mail to the lab
In Europe, 25% of inhabitants suffer from gut-associated diseases. It often starts with the 'Closed Gut' phenomenon. Practically, this means malabsorption and an 85% inactive enteric nervous system.
Furthermore, a Closed Gut creates an excess of noxae (ammonia derivatives), which cannot be adequately detoxified and cause shifts within the various biogenic amines. These ammonia derivatives occur under physiological conditions in animal organisms and have multiple functions; they act as neurotransmitters, co-factors or hormones.
In a Closed Gut, an increased toxin load causes a thickening of the connective tissue to protect the body. Figuratively speaking, the sluice gates close. This means that the therapeutic approach must be started differently than with Leaky Gut Syndrome.
The symptom pattern for a Closed Gut and Leaky Gut are similar, and therefore, based on symptom registration, the wrong therapeutic route can be chosen. For example, mucous membrane-strengthening measures (e.g., with glutamine) are counterproductive in a Closed Gut and often worsen the patient's symptoms. The diagnostics of the Closed Gut/ Leaky Gut screening and mucosal immunity provide clarity about which therapeutic route is necessary.
If you have opted for a Basic Gut Screening, the separate zonulin test provides insight into whether there is a Closed Gut or Leaky Gut.
The underlying condition or the clinical significance of this test is insufficiently supported within mainstream Dutch medicine.
Rationale for this test
Het concept 'Closed Gut' is geen erkend ziektebeeld binnen de Nederlandse reguliere geneeskunde en komt niet voor in NHG-standaarden of FMS-richtlijnen. De beschreven pathofysiologie (verdikking connectief weefsel door ammoniakderivaten, 85% inactief enteraal zenuwstelsel) heeft geen wetenschappelijke basis in de reguliere geneeskunde. Hoewel enkele individuele markers zoals calprotectine en alfa-1-antitrypsine wel klinisch gevalideerd zijn voor specifieke darmaandoeningen, is de combinatie en interpretatie binnen het 'Closed Gut versus Leaky Gut'-framework niet evidence-based.
Do not interpret a result from this test as a diagnosis, and always discuss with your GP which regular diagnostics are appropriate for your symptoms.
We recommend consulting these independent sources before ordering a preventive health check.
Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.
Independent information about preventive health checks from the National Institute for Public Health and the Environment.
Reliable patient information about illnesses and complaints from Dutch GPs (NHG).
Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.
Answers to what people usually want to know.
View instructionsFull instructions with visual guidanceAfter ordering we ship the kit to your home. You collect a small sample with the included scoop, keep it cool and return it in the envelope. You receive the result digitally by email.
Lay plastic film over the toilet or use a clean container. Scoop from the middle of the stool and avoid contact with urine or toilet water.
A small scoop with the included spoon is enough — about half a teaspoon. More is not better.
Maximum 24 to 48 hours in the fridge. Send as soon as possible and preferably early in the week, not just before the weekend.
Some analyses (like calprotectin) ask you to avoid NSAIDs or certain supplements 24-48 hours before collection. Check the instructions with your kit for the exact preparation for your test.
Stool analyses typically take about a week after the lab receives your sample. You get an email with a link to your digital result, including explanation per value.
In the included return envelope with free medical shipping. Drop it in the mailbox; the lab processes your sample as soon as it arrives. For some tests it's important to send it the same day — the instructions make this clear.
Feel free to contact us via WhatsApp, email or phone. We're happy to help you before, during or after your test. If the collection doesn't work, we'll arrange a solution or send new materials — no hassle.
Didn't find what you're looking for? Request a custom test
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