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BBloedCheckupLab made simple
  • Blood tests
    • Test packages
    • Hormones
    • Cardiovascular
    • Thyroid
    • Vitamins
    • Custom test request
    View all blood tests
  • At-home tests
    • Test packages
    • STDs
    • Hormones
    • Heart
    • Thyroid
    • Vitamins
    View all at-home tests
  • How it works
    • How it works
    • Locations
    • Laboratories
    • Fasting guidance
    • Shipping
  • Contact
    • Contact us
    • FAQ
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Blood draw

Expanded: Testosterone Replacement Therapy (TRT)

Testosterone, LH, FSH, estradiol, prolactin, blood values, complete liver function, kidney function, and lipid profile.

€ 235,00

Blood collection at collection point

Schedule your blood draw yourself

  1. 01

    Order your test

    After your order you receive instructions by email

  2. 02

    Schedule your appointment

    Make an appointment at a collection point near you

  3. 03

    Visit the collection point

    Blood collection at 1,000+ locations across the Netherlands

  4. 04

    Receive your result

    Digitally by email once the analysis is complete.

See how it works

Blood collection at collection point

How it works

See how it works
  1. 01

    Order your test

    After your order you receive instructions by email

  2. 02

    Schedule your appointment

    Make an appointment at a collection point near you

  3. 03

    Visit the collection point

    Blood collection at 1,000+ locations across the Netherlands

  4. 04

    Receive your result

    Digitally by email once the analysis is complete.

See how it works

What is Expanded TRT?

The Expanded TRT blood test is a comprehensive version of the standard TRT test that measures additional essential safety values for men considering or already using testosterone replacement therapy. This test adds important cardiovascular markers, more extensive liver function tests, and kidney function to the basic TRT markers. It is crucial for monitoring potential side effects and optimizing the safety of TRT treatment. This test provides a more complete picture of how your body responds to testosterone therapy and checks important organ systems that may be affected.

What is tested?

  • Testosterone (total) – The primary male sex hormone
  • Free testosterone – Biologically active form
  • LH (Luteinizing hormone) – Regulates testosterone production
  • FSH (Follicle-stimulating hormone) – Regulates sperm production
  • Oestradiol – Important oestrogen
  • Prolactin – Can inhibit testosterone production
  • Hemoglobin – Oxygen transport
  • Hematocrit (Ht) – Percentage of red blood cells
  • ALT – Liver enzyme
  • AST – Liver enzyme
  • Gamma-GT – Liver enzyme for bile ducts
  • Alkaline phosphatase – Liver and bone marker
  • Creatinine – Kidney function
  • eGFR – Estimated kidney function
  • Cholesterol (total) – Cardiovascular risk
  • HDL cholesterol – "Good" cholesterol
  • LDL cholesterol – "Bad" cholesterol
  • Triglycerides – Fats in blood

Why should you get an Expanded TRT test?

This comprehensive test is essential for safe TRT monitoring because testosterone therapy can affect various organ systems. The full lipid profile checks cardiovascular health because TRT can alter cholesterol levels. Extensive liver function tests (including alkaline phosphatase and gamma-GT in addition to ALT/AST) provide a more complete picture of liver strain. Kidney function (creatinine and eGFR) is important because TRT can stress the kidneys. This test is recommended at the start of TRT as a baseline, every 3-6 months during the first year of TRT, and then annually with stable values. Also suitable for dose adjustments or in case of new symptoms.

What does it indicate?

The results provide comprehensive insight into both the effectiveness and safety of TRT. This test measures:

  • Hormonal balance – Testosterone, LH, FSH, oestradiol, and prolactin
  • Cardiovascular risk factors – Complete lipid profile
  • Liver strain – Complete liver function tests
  • Kidney function – Creatinine and eGFR
  • Blood counts – Hemoglobin and hematocrit

This complete monitoring helps detect side effects early and optimize treatment safely.

What does a high level mean?

  • Elevated testosterone during TRT – May indicate an excessively high dosage that needs adjustment
  • Very high hematocrit (above 52-54%) – Dangerous and significantly increases thrombosis risk, possibly requiring phlebotomy
  • Elevated liver enzymes – May indicate liver strain due to testosterone
  • High LDL cholesterol and triglycerides – Increase cardiovascular risk and should be managed
  • Elevated oestradiol – Can cause gynecomastia and fluid retention

These abnormalities require dose adjustment or additional medication.

What does a low level mean?

  • Low testosterone during TRT – Indicates insufficient dosage that needs to be increased
  • Suppressed LH/FSH – Normal during TRT but confirms that natural production has ceased
  • Too low hematocrit – May indicate anaemia despite TRT
  • Low HDL cholesterol – Unfavourable for cardiovascular health
  • Low oestradiol – Can lead to joint pain and decreased bone density
  • Reduced kidney function – Requires dose adjustment

This comprehensive test helps to safely and effectively optimize TRT for maximum benefits with minimal risks.

  • Testosteron
  • Vrij testosteron
  • LH
  • FSH
  • Oestradiol
  • Prolactine
  • Hemoglobine
  • Hematocriet
  • ALAT
  • ASAT
  • Gamma-GT
  • Alkalische fosfatase
  • Kreatinine
  • eGFR
  • Cholesterol totaal
  • HDL-cholesterol
  • LDL-cholesterol
  • Triglyceriden

Indication-specific evidence

This test has clinical value for specific complaints or indications, but is not intended as screening without symptoms.

Rationale for this test

Deze uitgebreide bloedtest combineert hormonale markers en veiligheidsparameters die relevant zijn voor mannen die testosteron replacement therapie (TRT) overwegen of gebruiken. De individuele componenten (testosteron, leverfunctie, nierfunctie, lipidenprofiel, PSA) zijn gevestigde laboratoriumbepalingen binnen de Nederlandse reguliere geneeskunde. TRT zelf is een erkende behandeling voor hypogonadisme, maar vereist medische begeleiding en indicatiestelling door een arts. Deze test is niet bedoeld als screening zonder medische indicatie, maar als monitoring-instrument bij bestaande TRT-behandeling of bij verdenking op hypogonadisme onder medische supervisie.

Sources consulted

International scientific literature

  • An updated systematic review and meta-analysis of the effects of testosterone replacement therapy on erectile function and prostate - PMC
  • Background and research question - The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation - NCBI Bookshelf
  • The benefits and risks of testosterone replacement therapy: a review - PMC
  • Efficacy and safety of testosterone replacement therapy in men with hypogonadism: A meta-analysis study of placebo-controlled trials - PMC

Independent information sources

We recommend consulting these independent sources before ordering a preventive health check.

  • Client brochure PGO (NVvPG, September 2023)

    Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.

  • RIVM — Health tests

    Independent information about preventive health checks from the National Institute for Public Health and the Environment.

  • Thuisarts.nl

    Reliable patient information about illnesses and complaints from Dutch GPs (NHG).

  • Allesovertesten.nl (NVKC)

    Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.

Practical information

Frequently asked questions

How does it work from order to result?

After ordering we generate a referral letter and email you the instructions. You pick a collection point yourself and book an appointment there. Blood is drawn at the location, processed at the lab, and your result arrives digitally.

How quickly can I get tested?

Often within a few working days. How soon you can be seen depends on how busy the location is and the type of analysis. For specialist analyses we first ship collection materials, which takes a bit longer.

Do I need to book an appointment?

At most collection points yes. Some accept walk-ins. This is clearly indicated per location. You choose the location that works best for you.

Do I need to fast before the test?

That depends on the test. Whether fasting is required, and from what time, is clearly stated in the instructions you receive after ordering. No surprises at the counter.

When and how do I receive my result?

It varies per analysis: from same-day to a few working days. Standard values often come back quickly; analyses that go to an external lab can take a bit longer. You receive your laboratory report securely by email. It lists the measured values, units, reference ranges and any flags added by the laboratory.

Where can I go for collection?

We work with 1,000+ collection points across the Netherlands. After ordering you'll see which locations near you are available and you pick where you'd like to go.

View all frequently asked questions

Personal help

Contact us

WhatsAppWhatsApp+31 412 236 961E-mailinfo@bloedcheckup.nlCollection points1,000+ across the Netherlands

Weekdays 09:00 – 17:00 · Outside hours we reply a bit later

Didn't find what you're looking for?Request a custom test

Verified reviews

View allView all reviews

Client experiences

89% recommend us368 verified reviews

“Very positive experience”

From ordering to having my blood drawn, everything went smoothly and was well organised. I really appreciated being able to visit a blood collection location in my own town so quickly. I received clear instructions beforehand, and the results arrived promptly by email too. Very satisfied!

ElineVerified

“Good communication”

This company responds to questions thoroughly and promptly. The entire process, from requesting the test to having blood drawn and receiving the results, runs very smoothly. Overall, I am very satisfied!

Jacques QuipèreVerified

“Wide choice of tests, fast and affordable”

You can choose the tests yourself. Fast delivery and processing, clear instructions and affordable.

SMVerified

“I am satisfied with the service”

I received a referral by email, just like from a GP. I did not have to send anything by post and could quickly visit a local blood collection centre. The results were fast and clear. The price was good, not too expensive, and all messages were secure.

kraljicaVerified

“A very good experience”

A very good experience! I received quick answers to my questions, a custom blood test was put together, everything was arranged smoothly, and I could have my blood drawn by a healthcare professional nearby. The results were available within a few days. In short, very satisfied!

PhilVerified

“Very good customer service”

The customer service is very good. I had a complex request, which caused an issue at the blood collection centre. Customer service resolved it very well. They also offer a wide range of tests at a reasonable price.

Marc EekhoutVerified

“Everything was well organised”

Everything was well organised. The products were delivered within a few days and, after sending in the samples, the results arrived within a few days too. Communication and information throughout the process were clear and friendly.

martijnVerified

“Fantastic service”

Fantastic service! Very good customer service that responds quickly and thinks along with you. Good prices. I will definitely use BloedCheckup's services again.

kambalesVerified

“Very happy to have found this business”

Very happy to have found this business. We need to check our blood more often :) The process was easy. They sent me the kit at home, then I had to go to a clinic with the papers and they knew what they had to do. I got the results in less than a week.

DenisaVerified

“Smooth process and good support”

Amazing website experience. I ordered various tests for 2 people. We went to one of the supported centers and took samples. Also after the results were ready, I needed a letter from the laboratory and they prepared the letter for me in no time. Definitely recommended.

Majid HajiheidariVerified

“Amazing service!”

Received a packet with everything needed, went to a walk in clinic (Amsterdam DC Clinic) where my blood was drawn and I was out the door within 5 minutes, and then after posting the samples, received results 2 days later. Results were easy to understand as well. Amazing service, would highly recommend!

Trudi CoetzeeVerified

“Great customer service”

I ordered a test through bloedcheckup.nl but later realized I no longer needed it. I contacted their support team, and they were very quick, responsive, and helpful in handling my cancellation. The whole process was smooth and efficient. Great customer service!

Elif Göksu BecerikVerified
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