AMA; PBC serology.
Blood collection at collection point
After your order you receive instructions by email
Make an appointment at a collection point near you
Blood collection at 1,000+ locations across the Netherlands
The Anti-AMA Antibodies Blood Test is a laboratory test used to detect antimitochondrial antibodies (AMA) in the blood. AMA are specific antibodies directed against proteins in the mitochondria of cells. This test is particularly important for the diagnosis of Primary Biliary Cholangitis (PBC), an autoimmune disease affecting the liver.
This test is essential for people experiencing symptoms that may indicate PBC, such as fatigue, itching, dry eyes and mouth, and upper abdominal pain. Early detection of AMA can help establish the diagnosis of PBC, enabling early treatment to manage the progression of the disease.
A positive result for the Anti-AMA Antibodies Blood Test indicates the presence of AMA in the blood, which is a strong indication of PBC. It is a crucial component of the diagnosis, along with other clinical assessments and laboratory tests.
A positive result indicates the presence of AMA, which in most cases points to PBC. This result is an important diagnostic criterion for PBC and requires further evaluation and possible treatment by a specialist.
A negative result means that no AMA were detected in the blood sample. This may suggest the absence of PBC, but other factors and symptoms must also be considered. It is important to undergo a full medical evaluation if symptoms indicative of liver disease are present.
This test is included in Dutch healthcare guidelines and is regularly used for its respective indications.
Rationale for this test
Deze test is een gevestigde diagnostische bepaling voor Primaire Biliaire Cholangitis (PBC), een erkende auto-immuunziekte van de lever. De test heeft een hoge diagnostische nauwkeurigheid met een specificiteit van 98% en sensitiviteit van 84%. AMA-bepaling is wereldwijd de standaard-serologie voor PBC-diagnostiek en wordt in de Nederlandse klinische praktijk routinematig ingezet bij verdenking op deze leverziekte.
International scientific literature
We recommend consulting these independent sources before ordering a preventive health check.
Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.
Independent information about preventive health checks from the National Institute for Public Health and the Environment.
Reliable patient information about illnesses and complaints from Dutch GPs (NHG).
Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.
Answers to what people usually want to know.
After ordering we generate a referral letter and email you the instructions. You pick a collection point yourself and book an appointment there. Blood is drawn at the location, processed at the lab, and your result arrives digitally.
Often within a few working days. How soon you can be seen depends on how busy the location is and the type of analysis. For specialist analyses we first ship collection materials, which takes a bit longer.
At most collection points yes. Some accept walk-ins. This is clearly indicated per location. You choose the location that works best for you.
That depends on the test. Whether fasting is required, and from what time, is clearly stated in the instructions you receive after ordering. No surprises at the counter.
It varies per analysis: from same-day to a few working days. Standard values often come back quickly; analyses that go to an external lab can take a bit longer. You get an email with a link to your digital result, including a short explanation per value.
We work with 1,000+ collection points across the Netherlands. After ordering you'll see which locations near you are available and you pick where you'd like to go.
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Received a packet with everything needed, went to a walk in clinic (Amsterdam DC Clinic) where my blood was drawn and I was out the door within 5 minutes, and then after posting the samples, received results 2 days later. Results were easy to understand as well. Amazing service, would highly recommend!