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    View all tests
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Blood draw

Testosterone Replacement Therapy (TRT)

Testosterone, LH, FSH, Oestradiol, Prolactin, PSA, liver function, and blood values. For men with low testosterone or TRT monitoring.

€ 175,00

Blood collection at collection point

How it works

  1. 01

    Order your test

    After your order you receive instructions by email

  2. 02

    Schedule your appointment

    Make an appointment at a collection point near you

  3. 03

    Visit the collection point

    Blood collection at 1,000+ locations across the Netherlands

  4. 04

    Receive your result

    Digitally by email once the analysis is complete.

See how it works

Blood collection at collection point

How it works

See how it works
  1. 01

    Order your test

    After your order you receive instructions by email

  2. 02

    Schedule your appointment

    Make an appointment at a collection point near you

  3. 03

    Visit the collection point

    Blood collection at 1,000+ locations across the Netherlands

  4. 04

    Receive your result

    Digitally by email once the analysis is complete.

See how it works

About PSA testing: screening vs. indication

PSA testing is not recommended by the Dutch College of General Practitioners (NHG) or the Health Council as screening in men without complaints. The test can lead to follow-up tests and treatment for findings that would not have posed a clinical problem (overtreatment).

The test is however useful for specific indications: urinary complaints (LUTS), a previously elevated PSA value, or a familial background of prostate cancer. Please discuss the wish for this test with your GP first so results and next steps can be properly integrated.

Source: guidelines from the NHG and advice from the Health Council of the Netherlands on PSA testing and prostate cancer screening.

What is the Testosterone Replacement Therapy (TRT) Blood Test?

The TRT Blood Test is a comprehensive blood analysis specifically developed to check if you could benefit from testosterone replacement therapy. This test measures not only your testosterone levels, but also important hormones that regulate testosterone production, as well as markers for liver, blood, and prostate health. It is essential for men with symptoms of low testosterone such as fatigue, decreased libido, mood swings, and loss of muscle mass. If suitable, a physician can directly prescribe and guide TRT.

What is tested?

  • Testosterone (total) – The primary male sex hormone
  • LH (Luteinizing hormone) – Hormone that stimulates testosterone production in the testes
  • FSH (Follicle-stimulating hormone) – Regulates sperm production
  • Estradiol – Main estrogen, converted from testosterone
  • Prolactin – Hormone that can inhibit testosterone production at elevated levels
  • PSA (Prostate-specific Antigen) – Marker for prostate health
  • Hemoglobin – Oxygen-transporting protein in red blood cells
  • Hematocrit (Ht) – Percentage of red blood cells in blood
  • ALT (Alanine transaminase) – Liver enzyme
  • AST (Aspartate transaminase) – Liver enzyme
  • Gamma-GT – Liver enzyme for bile duct function
  • Alkaline phosphatase – Enzyme for liver and bone health

Why should you get the TRT Blood Test?

This test is crucial for men considering starting TRT or those already using TRT and wishing to monitor their levels. Symptoms of low testosterone such as chronic fatigue, decreased libido, erectile dysfunction, loss of muscle mass, increase in body fat, and depressive feelings can significantly reduce quality of life. The test provides a complete picture of your hormonal status and checks important safety markers such as liver function, blood counts, and prostate health that are important for TRT treatment.

What does it indicate?

The results provide comprehensive insight into your hormonal health and suitability for TRT. This test measures:

  • Testosterone levels and regulation – Low testosterone with low LH/FSH indicates secondary hypogonadism (brain), low testosterone with high LH/FSH indicates primary hypogonadism (testes)
  • Estradiol – Elevated levels can cause side effects
  • Prostate health – PSA levels are essential because TRT can affect the prostate
  • Liver and blood values – Important for safe treatment

This information helps physicians develop a personalized TRT plan with optimal dosage and monitoring.

What does a high level mean?

  • High testosterone levels during TRT – May indicate an excessively high dosage
  • Elevated hematocrit – A known side effect of TRT that increases the risk of blood clots
  • Elevated liver enzymes – May indicate liver strain
  • High PSA value – Requires further investigation for prostate problems
  • Elevated estradiol – Can lead to fluid retention, gynecomastia, and mood swings

These values help to safely optimize treatment.

What does a low level mean?

  • Low testosterone levels – Confirm the diagnosis of hypogonadism and justify TRT treatment
  • Low LH/FSH with low testosterone – Indicate a problem in the pituitary or hypothalamus
  • Too low hematocrit during TRT – May indicate anemia
  • Low estradiol – Can lead to joint problems and decreased bone density

This information helps physicians develop a personalized TRT plan with optimal dosage and monitoring.

Indication-specific evidence

This test has clinical value for specific complaints or indications, but is not intended as screening without symptoms.

Rationale for this test

Deze bloedtest meet hormonen en veiligheidsmarkers die relevant zijn voor testosteron replacement therapie (TRT). TRT zelf is een gevestigde behandeling binnen de reguliere geneeskunde voor mannen met bewezen hypogonadisme (testosterontekort). De test is echter niet bedoeld als screening zonder klachten of medische indicatie. Voor het starten van TRT is altijd medische begeleiding noodzakelijk, inclusief grondige diagnostiek en afweging van risico's zoals cardiovasculaire effecten en prostaatgezondheid.

Sources consulted

Dutch clinical guidelines and healthcare organisations

  • Diagnostiek van overgewicht en obesitas bij volwassenen - Richtlijn
  • Fertiliteit en osteoporose na Hodgkinlymfoom - Richtlijn

International scientific literature

  • Cardiovascular Effects of Testosterone Replacement Therapy in Hypogonadal Men: A Systematic Review of Lipid Profiles, Inflammatory Markers, and Vascular Function - PMC
  • Benefits of Testosterone Hormone in the Human Body: A Systematic Review - PMC

Independent information sources

We recommend consulting these independent sources before ordering a preventive health check.

  • Client brochure PGO (NVvPG, September 2023)

    Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.

  • RIVM — Health tests

    Independent information about preventive health checks from the National Institute for Public Health and the Environment.

  • Thuisarts.nl

    Reliable patient information about illnesses and complaints from Dutch GPs (NHG).

  • Allesovertesten.nl (NVKC)

    Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.

Frequently asked questions

Answers to what people usually want to know.

How does it work from order to result?

After ordering we generate a referral letter and email you the instructions. You pick a collection point yourself and book an appointment there. Blood is drawn at the location, processed at the lab, and your result arrives digitally.

How quickly can I get tested?

Often within a few working days. How soon you can be seen depends on how busy the location is and the type of analysis. For specialist analyses we first ship collection materials, which takes a bit longer.

Do I need to book an appointment?

At most collection points yes. Some accept walk-ins. This is clearly indicated per location. You choose the location that works best for you.

Do I need to fast before the test?

That depends on the test. Whether fasting is required, and from what time, is clearly stated in the instructions you receive after ordering. No surprises at the counter.

When and how do I receive my result?

It varies per analysis: from same-day to a few working days. Standard values often come back quickly; analyses that go to an external lab can take a bit longer. You get an email with a link to your digital result, including a short explanation per value.

Where can I go for collection?

We work with 1,000+ collection points across the Netherlands. After ordering you'll see which locations near you are available and you pick where you'd like to go.

View all frequently asked questions

Didn't find what you're looking for? Request a custom test

Need help?

We're here for you. Send a message and we'll respond as soon as we can.

WhatsAppWhatsApp+31 412 236 961E-mailinfo@bloedcheckup.nlCollection points1,000+ across the Netherlands

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Client experiences

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Klantenservice was erg behulpzaam in het beantwoorden van mijn vragen. Ik had ook een extra setje buizen nodig als back-up en dat was geen probleem. Ik had een groot test panel besteld, maar de resultaten waren binnen 1 week binnen. Rapport zag er netjes uit.

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Fijn bedrijf met geweldig veel opties om zelfstandig je gezondheid in het oog te houden, als sporter een must want de dokters hebben toch geen verstand van wat relevant en anders is voor sport. Ook zeer tevreden over Stijn zelf! Aangename kerel en goed bereikbaar voor vragen en hulp tijdens bestellen :D

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My experience was very positive. I needed to pass several very specific tests. They provide 24/7 customer support. They were friendly and prompt.

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“Top!”

Snelle en makkelijke afhandeling. Duidelijke instructies en binnen anderhalve dag al resultaat binnen. Top service!

ZerinaVerified

“Amazing service!”

Received a packet with everything needed, went to a walk in clinic (Amsterdam DC Clinic) where my blood was drawn and I was out the door within 5 minutes, and then after posting the samples, received results 2 days later. Results were easy to understand as well. Amazing service, would highly recommend!

Trudi CoetzeeVerified
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