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All tests

Allergy and intolerance · Blood

IgE antibodies shrimp

Antibodies against shrimp protein; shows whether the immune system is sensitive to shrimp, not whether you get symptoms from it.

At a glance

  • Measured in blood
  • In 2 test panels
  • No special preparation

IgE antibodies shrimp

  • Explanation
  • Result
  • Reliability
  • Who it is for
  • Test panels
  • Sources

Explanation

IgE antibodies shrimp: what is measured?

Shrimp belong to the crustaceans, as do crab, lobster and crayfish; crustaceans must be listed as an allergen on food packaging. Symptoms can come from eating, but also from touching, from breathing in steam while crustaceans are being cooked, or from oil containing traces of crustaceans. This test measures the amount of IgE antibodies against the proteins in shrimp in the blood, in kU/l. The body only makes these antibodies after it has previously been in contact with the allergen; this is called sensitization. Other crustaceans and mollusks, such as mussels, are not measured separately.

What can it detect?

  • Sensitization to shrimp: the body has made IgE antibodies against shrimp
  • Support in working out a suspected allergy to shrimp, together with the history of the symptoms
  • Support in answering whether a reaction after eating, touching or cooking shrimp fits an allergy

Result

What does the result mean?

IgE antibodies shrimp too high

A value above the cut-off means that you have IgE antibodies against shrimp: sensitization. That is not the same as an allergy: in one study in the Dutch medical specialists' guideline (FMS), more than half of the people without a shrimp allergy still tested positive. Shrimp contain the protein tropomyosin, which is also found in house dust mite, mealworms and mollusks; according to Stichting Voedselallergie, this causes cross-reactions with house dust mite and mealworms. According to the same foundation, 50 to 75 in 100 people with a shrimp allergy also react to mollusks, such as mussels, oysters, squid and snails. In case of doubt, an allergist can have antibodies against individual shrimp proteins measured. The level of the value says little about how severe a reaction would be.

IgE antibodies shrimp too low

A value below the cut-off means that no IgE antibodies against this allergen were found. An IgE-mediated allergy to this allergen is then much less likely, although it is not completely ruled out. Symptoms can also come from another allergen that was not tested, or have a non-allergic cause.

After an abnormal result

The GP mainly looks at the history: which symptoms, when and where they occur and after contact with what. With a positive result and matching symptoms, advice usually follows to limit contact with the allergen and, if needed, medication. With a severe reaction, in case of doubt or with symptoms that are not brought under control this way, a referral to an allergist, pediatrician, ENT specialist or lung specialist may follow.

Reliability

How reliable is the test?

A positive IgE result shows sensitization, not allergy: it only says that there are antibodies, not that you get symptoms from them. The Dutch medical specialists' guideline (FMS) on upper airway allergy says this literally and recommends choosing a test for single allergens based on the history of the symptoms; for food allergy, the FMS guideline on food challenge testing calls the history of the symptoms the cornerstone of diagnosis and a food challenge in hospital the gold standard. The result therefore only means something if it fits when, where and after contact with what you get symptoms. A positive result without symptoms is not treated.

What can affect the result?

  • Sensitization without symptoms is common; the result can only be interpreted together with the history of the symptoms.
  • Related allergens can recognize each other's antibodies (cross-reaction), for example pollen and nuts or fruit; a positive result then does not mean that this particular allergen causes the symptoms.
  • The test measures all proteins from the allergen source together; testing for individual proteins (components) can say more in case of doubt.
  • Laboratories use different measurement methods and cut-off values; results from different labs cannot be compared one to one.

Who it is for

Who is the test useful for?

Useful for

Useful with a clear reaction after eating, touching or cooking shrimp or other crustaceans, such as itching and swelling in the mouth and throat, hives, vomiting or shortness of breath; symptoms usually start within an hour. In people with a house dust mite allergy who eat shrimp normally, the result can be positive due to cross-reaction without a shrimp allergy. In people who eat shrimp without symptoms, the test adds nothing.

How common is it?

According to Stichting Voedselallergie, about 1 in 100 people have an allergy to fish or crustaceans. Crustacean allergy is most common in adults and, after peanut and nuts, is the most common cause of a severe allergic reaction (anaphylaxis). Someone who has a crustacean allergy will probably not outgrow it.

Stichting Voedselallergie

Get tested

IgE antibodies shrimp: test panels

IgE antibodies shrimp is part of these test panels. You order online and have your blood drawn at a collection point or collect the sample at home.

  • Shrimp allergy (IgE shrimp)

    Blood draw

    Shrimp allergy (IgE shrimp)

    Measures IgE antibodies against proteins in shrimp. For anyone with allergic symptoms after eating, touching or cooking shrimp.

    € 36,00

  • Follow-up test fish and seafood: 5 types separately

    Blood draw · 5 analyses

    Follow-up test fish and seafood: 5 types separately

    Measures IgE separately against cod, tuna, salmon, shrimp and mussel. For finding out the cause after a positive screen and a reaction.

    € 96,00

Evidence

Sources

This explanation is based on Dutch guidelines and independent information. It is general information, not a diagnosis. Discuss an abnormal result with your GP.

More about risks and results
  • NVKC, allesovertesten.nl: Allergie (RAST)
  • FMS Richtlijnendatabase: Allergie van de bovenste luchtwegen, module Aanvullende diagnostiek
  • FMS Richtlijnendatabase: Voedselprovocatie, module Plaatsbepaling diagnostiek voedselallergie
  • Thuisarts.nl: Ik heb allergie
  • NHG-Standaard Voedselovergevoeligheid en coeliakie (M47)
  • Stichting Voedselallergie: Schaaldieren
  • Thuisarts.nl: Ik denk dat ik niet tegen bepaald voedsel kan

More explanations

Other tests: Allergy and intolerance

  • Alpha-gal antibodies
  • Animal dander mix (allergy)
  • Fish and seafood mix (allergy)
  • Food allergen screen (fx5)
  • Grass pollen mix (allergy)
  • House dust mite specific IgE
  • IgE allergen mix, large
  • IgE allergen mix, small
  • IgE antibodies apple
  • IgE antibodies celery
  • IgE antibodies hazelnut
  • IgE antibodies peanut
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