


Holotranscobalamin (HOLO-TC) is a biomarker that measures the amount of vitamin B12 in the body that is directly available for cellular uptake. It is an early indicator of vitamin B12 deficiency because it only reflects the portion of vitamin B12 that can be actively used by the body.
Testing HOLO-TC is useful for people experiencing symptoms that may indicate a vitamin B12 deficiency, such as fatigue, weakness, memory problems, or neurological changes. It is also valuable for individuals at risk of vitamin B12 deficiency, such as the elderly, vegans, and those with certain gastric conditions or who use certain medications.
HOLO-TC levels indicate the amount of readily available vitamin B12 in the blood. This helps determine whether the body has sufficient vitamin B12 for essential functions such as DNA synthesis, blood cell production, and nerve maintenance.
A high level of HOLO-TC is generally uncommon and less frequently associated with health problems. However, in rare cases, it may indicate certain medical conditions or the use of vitamin B12 supplements.
A low level of HOLO-TC indicates a deficiency of available vitamin B12 in the body. This can lead to various health issues, including anemia, nerve damage, fatigue, and cognitive impairments.
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After ordering we ship the collection kit to your home. You prick your fingertip, collect a few drops of blood, return it in the envelope, and receive your result digitally by email.
A small prick on your fingertip lets you collect a few drops into a tube. The instructions include step-by-step photos and video, so no guessing required.
In the included return envelope with free shipping. Just drop it in the mailbox; the lab processes your sample as soon as it arrives.
Active B12 (holotranscobalamin); sensitive marker for B12 status.
€55.00EUR
Usually 2 to 5 working days after the lab receives your sample. You get an email with a link to your digital result, including explanation per value.
No stress. If it doesn't work we'll help you out. Contact us and we'll arrange a solution or send new materials. No hassle.


