


Antimitochondrial antibodies (AMA) are autoantibodies directed against specific proteins in the mitochondria, the energy factories of the cell. The presence of AMA in the blood is an important biomarker for the diagnosis of Primary Biliary Cholangitis (PBC), an autoimmune disease of the liver that damages the small bile ducts.
Testing for AMA is useful for diagnosing PBC, especially in individuals exhibiting symptoms such as fatigue, itching, dry eyes and mouth, and discomfort in the upper right abdomen. Early diagnosis and treatment of PBC can delay the progression of the disease and improve quality of life.
The presence of AMA in the blood is a strong indicator for PBC. Although not everyone with AMA develops PBC, the majority of patients with PBC have high levels of AMA. It is an important diagnostic tool in combination with other clinical findings.
A positive AMA result indicates the presence of antimitochondrial antibodies in the blood, which can be a strong indication of PBC. It is important to combine this result with other diagnostic tests and clinical evaluation to definitively diagnose PBC.
A negative result means that AMA antibodies were not detected in the blood. Although this may suggest that someone likely does not have PBC, it does not fully rule out the disease, especially if symptoms are present. Other tests may be necessary for a full evaluation.
Answers to what people usually want to know.
After ordering we generate a referral letter and email you the instructions. You pick a collection point yourself and book an appointment there. Blood is drawn at the location, processed at the lab, and your result arrives digitally.
Usually very quickly. Collection points typically have slots within a few days, sometimes even same-day. It depends on how busy the location is. For a few specialist analyses we first ship collection materials, which takes a bit longer.
At most collection points yes. Some accept walk-ins. This is clearly indicated per location. You choose the location that works best for you.
AMA screening; cholestasis/PBC.



€40.95EUR
That depends on the test. Whether fasting is required, and from what time, is clearly stated in the instructions you receive after ordering. No surprises at the counter.
It varies per analysis: from same-day to a few working days. Standard values often come back quickly; analyses that go to an external lab can take a bit longer. You get an email with a link to your digital result, including a short explanation per value.
We work with 1,000+ collection points across the Netherlands. After ordering you'll see which locations near you are available and you pick where you'd like to go.
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