AST; liver and muscle enzyme.
Blood collection at collection point
After your order you receive instructions by email
Make an appointment at a collection point near you
Blood collection at 1,000+ locations across the Netherlands
AST (GOT) is an enzyme found in various tissues of the body, including the liver, heart, kidneys, muscles, and brain. It plays a role in amino acid metabolism. Measurements of AST levels in the blood are used to assess liver health and to identify damage to or diseases of the liver and other organs.
An AST test is relevant for people who show symptoms of liver disease, such as jaundice, fatigue, or abdominal pain, or for people who have been exposed to factors that can cause liver disease, such as alcohol misuse, hepatitis viruses, or the use of certain medications. It is also useful for monitoring liver function in people with known liver conditions.
Elevated AST levels in the blood may indicate liver damage or disease, as well as damage to other organs where the enzyme is present. AST is often measured in combination with other enzymes, such as ALT (alanine aminotransferase), to get a more complete picture of liver function.
A high level of AST may indicate liver inflammation, damage, or necrosis. It can also indicate damage to other organs, such as the heart or muscles. The specific cause of the elevation can vary and requires further investigation.
A low or normal level of AST in the blood is usually a sign of good liver function and the absence of significant damage to the organs where AST is found.
This test is included in Dutch healthcare guidelines and is regularly used for its respective indications.
Rationale for this test
ASAT (GOT) is een standaard-bepaling in Nederlandse zorgrichtlijnen voor het beoordelen van leverfunctie en het opsporen van leverschade. De test wordt routinematig gebruikt bij verdenking op leveraandoeningen, alcoholgerelateerde schade, en bij monitoring van bekende leverziekte. De klinische betekenis is goed onderbouwd.
Dutch clinical guidelines and healthcare organisations
International scientific literature
We recommend consulting these independent sources before ordering a preventive health check.
Brochure on preventive health checks: careful choice, reliability, pros and cons, checklist.
Independent information about preventive health checks from the National Institute for Public Health and the Environment.
Reliable patient information about illnesses and complaints from Dutch GPs (NHG).
Public-facing website of the Dutch Society for Clinical Chemistry with explanations of blood tests and laboratory values.
Answers to what people usually want to know.
After ordering we generate a referral letter and email you the instructions. You pick a collection point yourself and book an appointment there. Blood is drawn at the location, processed at the lab, and your result arrives digitally.
Often within a few working days. How soon you can be seen depends on how busy the location is and the type of analysis. For specialist analyses we first ship collection materials, which takes a bit longer.
At most collection points yes. Some accept walk-ins. This is clearly indicated per location. You choose the location that works best for you.
That depends on the test. Whether fasting is required, and from what time, is clearly stated in the instructions you receive after ordering. No surprises at the counter.
It varies per analysis: from same-day to a few working days. Standard values often come back quickly; analyses that go to an external lab can take a bit longer. You get an email with a link to your digital result, including a short explanation per value.
We work with 1,000+ collection points across the Netherlands. After ordering you'll see which locations near you are available and you pick where you'd like to go.
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