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BloedCheckup
  • Tests
    • Test packages
    • Hormones
    • Cardiovascular
    • Thyroid
    • Vitamins
    • STD test guide
    • Custom test request
    View all tests
  • At-home tests
    • Fingerstick
    • Urine
    • Stool
    • Saliva
    • Hair
    • Swab
    View all at-home tests
  • How it works
    • How it works
    • Locations
    • Laboratories
    • Fasting guidance
    • Shipping
    • Blog
  • About us
    • About us
    • Customer reviews
    • For business
  • Contact
    • FAQ
    • Contact us
  1. Home
  2. Tests
  3. Zonuline feces
BloedCheckup

Professional blood tests without GP referral. Partnership with ISO certified laboratories for reliable results.

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Test kit

Feces Home Test

  • Collect a small sample with the spatula
  • Place the sample in the provided tube
  • Return via medical mail to the lab

Zonuline

Meet zonuline in ontlasting. Indicatie voor darmwandintegriteit en leaky gut syndroom.

Test kit

Feces Home Test

  • Collect a small sample with the spatula
  • Place the sample in the provided tube
  • Return via medical mail to the lab

Instruction video

Zonuline is een proteïne, dat actief is in het darmepitheel. Zonuline reageert op blootstelling aan gliadine en pathogene bacteriën. Gliadine vormt samen met glutenine het eiwit gluten.

Zodra zonuline wordt vrijgemaakt door de epitheelcellen, wordt dit gesignaleerd door Immunoglobuline A, waarna een reactie volgt van de darmwand. De verbindingseiwitten (tight junctions) tussen de cellen van de darmwand verslappen of verbreken. De gliadinen of pathogene bacteriën kunnen nu de darmwand passeren, waarna dendritische cellen via de antigeen-presenterende cellen, een T-celactivatie uitlokken.
Deze immuunrespons veroorzaakt inflammatie van de cellen van de darmwand, waarna zonuline, tight junction-eiwitten, pathogenen, bacteriële lipopolysaccharides en ontstekingsmediërende cytokinen vanuit de darmen het lamina propria kunnen binnendringen. Vervolgens komen deze stoffen in de bloedbaan, waardoor ze neuroinflammatie kunnen uitlokken.

Frequently asked questions

Answers to what people usually want to know.

How does the home test work from A to Z?

After ordering we ship the complete home test to your home. You collect the sample following the instructions, return it in the envelope, and receive your result digitally by email.

How do I collect the sample myself?

The kit contains everything you need plus step-by-step instructions. Take your time and read everything before you start. You can't go wrong.

How do I return the sample?

In the included return envelope with free shipping. Send it as soon as possible after collection for the best result.

When and how do I receive my result?
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€140.00EUR

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  • Home collection, test kit by mail
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Usually 2 to 5 working days after the lab receives your sample. You get an email with a link to your digital result, including explanation per value.

What if I have questions or doubts?

Feel free to contact us via WhatsApp, phone or email. We're happy to help you before, during or after your test.

Need help?

We're here for you. Send a message and we'll respond as soon as we can.

WhatsApp+31 412 236 961E-mailinfo@bloedcheckup.nl

Weekdays 09:00 – 17:00 · Outside hours we reply a bit later

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