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    View all at-home tests
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All tests

Vitamins, minerals and amino acids · Blood

Vitamin B5 (pantothenic acid)

The amount of pantothenic acid in the blood; a deficiency is very rare and the blood value is a mediocre measure of it.

At a glance

  • Measured in blood
  • In 1 test panel
  • No special preparation

Vitamin B5 (pantothenic acid)

  • Explanation
  • Result
  • Reliability
  • Who it is for
  • Test panels
  • Sources

Explanation

Vitamin B5 (pantothenic acid): what is measured?

Pantothenic acid (vitamin B5) is a water-soluble vitamin. The body uses it to build coenzyme A, a helper substance needed in a great many steps of metabolism, especially in releasing energy from fatty acids and in building up and breaking down proteins and fats. Pantothenic acid is found in meat, eggs, whole grain products, legumes, milk, vegetables and fruit. Most of it in the blood is in the red blood cells as coenzyme A; the test usually measures the free pantothenic acid in serum or plasma.

What can it detect?

  • A very rare deficiency of pantothenic acid, for example with long-term severe malnutrition
  • A high intake from supplements

Result

What does the result mean?

Vitamin B5 (pantothenic acid) too high

A high value is almost always due to a supplement or a multivitamin. The body passes any excess in the urine. No diseases are known to go with a high value; only at doses of tens of grams per day can diarrhea occur, and such amounts are not found in ordinary supplements.

Vitamin B5 (pantothenic acid) too low

A low value is rare in the Netherlands. Pantothenic acid is found in almost all foods, so a deficiency practically only develops with long-term severe malnutrition. With a long-lasting and severe deficiency, a burning or painful feeling in the feet has been described. Tiredness, stress or burnout are not known consequences of a low pantothenic acid; a low result therefore does not explain those symptoms.

After an abnormal result

An abnormal value usually does not lead to further tests on its own. If there are signs of malnutrition, the GP looks at eating habits, weight history and other nutrients, and refers to a dietitian if needed.

Reliability

How reliable is the test?

What an abnormal value means has been little studied, also in people with tiredness. The amount in serum mainly follows the intake of the last few days and is a mediocre measure of the body's stores; research therefore usually looks at excretion in the urine or at the level in red blood cells. There is no dietary requirement for pantothenic acid, only an adequate intake set by the Health Council of the Netherlands, and there is no agreed cut-off below which a deficiency is said to exist.

What can affect the result?

  • Supplements and multivitamins raise the value sharply; stop them well before the blood draw if you want to measure your usual situation.
  • The result follows the intake of the last few days and says little about the stores in the cells.
  • Pantothenic acid is not stable in blood; delayed or warm transport lowers the measured value.
  • Measurement methods and reference values differ between laboratories and are not standardized.

Who it is for

Who is the test useful for?

Useful for

In adults with a varied diet, the result adds nothing. Even with long-lasting tiredness it says little: according to the guideline on chronic fatigue syndrome, it has not been shown that supplements reduce those symptoms. With long-term severe malnutrition or tube feeding, a doctor looks at the diet as a whole, not at this single value.

How common is it?

A deficiency of pantothenic acid is very rare in the Netherlands, because the vitamin is found in almost all foods. There are no Dutch figures on how often a low blood value is found, because no population study has been done on it.

The Netherlands Nutrition Centre (Voedingscentrum) and the Health Council of the Netherlands (adequate intake); no Dutch registration figure available

Drawbacks and risks

  • A low value without symptoms can cause unnecessary worry or lead to unnecessary further tests.
  • A low result can wrongly explain symptoms such as tiredness, so that another cause is found later.

Get tested

Vitamin B5 (pantothenic acid): test panels

Vitamin B5 (pantothenic acid) is part of these test panels. You order online and have your blood drawn at a collection point or collect the sample at home.

  • Pantothenic Acid - Vitamin B5 (fingerstick)

    Fingerstick

    Pantothenic Acid - Vitamin B5

    Measure vitamin B5 via finger prick. Important for energy production and hormone balance.

    € 165,00

Evidence

Sources

This explanation is based on Dutch guidelines and independent information. It is general information, not a diagnosis. Discuss an abnormal result with your GP.

More about risks and results
  • Voedingscentrum: Pantotheenzuur (vitamine B5)
  • Thuisarts.nl: Heb ik extra vitamines nodig?
  • FMS Richtlijnendatabase, richtlijn Chronisch vermoeidheidssyndroom: Dieetinterventies en supplementen

More explanations

Other tests: Vitamins, minerals and amino acids

  • AC/FC ratio
  • Acylcarnitine
  • Alanine
  • Antibodies against intrinsic factor
  • Arginine
  • Calcium
  • Calcium (albumin-corrected)
  • Carnitine, free
  • Carnitine, total
  • Coenzyme Q10
  • Copper
  • Folic acid
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