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All tests

Gut · Stool

Proteins (feces)

The amount of protein in the stool; gives an impression of protein digestion, but depends heavily on diet.

At a glance

  • Measured in stool
  • In 1 test panel
  • No special preparation

Proteins (feces)

  • Explanation
  • Result
  • Reliability
  • Who it is for
  • Test panels
  • Sources

Explanation

Proteins (feces): what is measured?

Protein from food is broken down in the stomach and small intestine into small building blocks (amino acids) that the gut absorbs. The stool also contains protein from gut cells, mucus, bacteria and sometimes blood. The laboratory measures how much protein in total is in a stool sample.

What can it detect?

  • A sign of incomplete protein digestion or protein loss through the bowel wall

Result

What does the result mean?

Proteins (feces) too high

A raised value can be caused by a protein-rich diet or fast passage through the gut. It may also fit too little digestive juice from the pancreas, or protein leaking from an irritated or inflamed bowel wall. The result alone does not say what the cause is. For protein loss through the gut, the hospital uses a different test (alpha-1 antitrypsin in the stool).

Proteins (feces) too low

A low value means little protein in the stool and fits good protein digestion. A low value has no further meaning.

After an abnormal result

Without symptoms, an abnormal result from this test usually needs no follow-up. With symptoms that fit poor digestion, the GP can request pancreatic elastase in the stool or a blood test for celiac disease, and if needed refer you to a gastroenterologist or internist (specialist in internal medicine).

Reliability

How reliable is the test?

Food remnants in a single stool sample mainly say something about what you have eaten and how quickly the food passed through the gut. How well the result shows or rules out poor digestion has not been well studied, neither in people without symptoms nor in people with bowel symptoms. If poor fat digestion (malabsorption) is suspected, the specialist may have fat measured in stool collected over a few days. For pancreatic function, pancreatic elastase in the stool has been studied better.

What can affect the result?

  • Food in the days before sample collection (fat, meat, raw vegetables, legumes, dairy, sugars) largely determines the result.
  • Diarrhea or, on the contrary, constipation changes the result, because the speed through the gut determines how much is digested.
  • One stool sample gives a snapshot; the composition differs from day to day.
  • Medicines such as laxatives, antibiotics, stomach acid inhibitors, pancreatic enzymes and weight-loss medicines that block fat absorption (orlistat) affect the result.

Who it is for

Who is the test useful for?

Useful for

Because diet strongly determines the result, this test says little in people without symptoms, and even with symptoms it does not identify a cause. With symptoms that may fit poor digestion, such as long-lasting fatty or mushy stools, unintended weight loss or long-lasting diarrhea, testing through the GP is the right route. Pancreatic elastase in the stool and a blood test for celiac disease are then more targeted first tests. With blood in the stool, unintended weight loss or new bowel symptoms after the age of 50, this test is no substitute for a visit to the GP.

How common is it?

There are no Dutch figures on how often an abnormal result for these tests occurs. Bowel symptoms themselves are common: according to the guideline, irritable bowel syndrome affects about 4 in 100 adults. Conditions in which food is truly poorly digested, such as chronic inflammation of the pancreas, are much rarer.

Dutch medical specialists' guidelines (FMS) on irritable bowel syndrome (NHG and NVMDL) and chronic pancreatitis

Get tested

Proteins (feces): test panels

Proteins (feces) is part of these test panels. You order online and have your blood drawn at a collection point or collect the sample at home.

  • Bile Acids

    Stool

    Bile Acids

    Analysis of fats, water content, proteins, starch, sugar, and bile acids in stool.

    € 95,00

Evidence

Sources

This explanation is based on Dutch guidelines and independent information. It is general information, not a diagnosis. Discuss an abnormal result with your GP.

More about risks and results
  • FMS Richtlijnendatabase: Prikkelbaredarmsyndroom, module Diagnostiek PDS
  • NHG-Standaard Prikkelbaredarmsyndroom (PDS)
  • NVKC, allesovertesten.nl: Elastase
  • NVKC, allesovertesten.nl: Trypsine
  • Thuisarts.nl: Ik heb diarree

More explanations

Other tests: Gut

  • Acetate and propionate production
  • Acetate- and propionate-forming bacteria
  • Acetic acid (feces)
  • Acetic acid, relative (feces)
  • Akkermansia, activity
  • Alpha-1 antitrypsin (feces)
  • Anti-gliadin IgA (feces)
  • Anti-transglutaminase IgA (feces)
  • Aspergillus fumigatus (feces)
  • Aspergillus niger (feces)
  • Bacteroides group, activity
  • Beta-defensin 2 (feces)
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