
Blood draw
Magnesium
Serum magnesium; electrolyte balance.
€ 32,00
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Vitamins, minerals and amino acids · Blood
The magnesium in your blood; mainly shows large deficiencies or excesses and says little about the store in your body.
At a glance
Explanation
Magnesium is a mineral needed for muscles, nerves, bones and energy production in cells. About half is in the bones and the rest mainly in cells, muscles and organs; only about 1 percent is in the blood. The intestines and kidneys keep the amount in the blood within narrow limits by absorbing and excreting more or less. This analysis measures the magnesium in serum.
Result
According to the Dutch Society for Clinical Chemistry (NVKC), a raised magnesium is rarely caused by diet. It is usually due to reduced kidney function, which makes the body less able to get rid of magnesium, or to magnesium from laxatives or high-dose supplements. Dehydration can also raise the value. A slightly raised value usually causes no symptoms. With a finger prick or a difficult blood draw, damaged blood cells (hemolysis) can release magnesium, making the result falsely high.
A low magnesium mainly results from loss or poor absorption: prolonged diarrhea, a lot of alcohol, malnutrition, bowel diseases such as Crohn's disease, water pills (diuretics), long-term use of stomach acid inhibitors (proton pump inhibitors) and poorly controlled diabetes. According to Het Acute Boekje of the Dutch internists, symptoms usually only appear at a strongly low value (below 0.5 mmol/l), often because potassium and calcium then also fall: muscle weakness, trembling, cramps and heart rhythm disorders. Vague symptoms such as tiredness or muscle cramps usually have another cause; according to Thuisarts, magnesium does not help against nighttime calf cramps, except sometimes during pregnancy. A normal value does not rule out a small deficiency in the cells.
With a low magnesium, the GP looks at medicines (water pills, stomach acid inhibitors), alcohol use and bowel symptoms, and usually also measures potassium, calcium and kidney function. With a raised magnesium, kidney function is checked and the use of laxatives or supplements is asked about.
Reliability
The measurement itself is reliable, but serum magnesium poorly reflects the store in the body, because only about 1 percent of the magnesium is in the blood and the body keeps that value stable. The Netherlands Nutrition Centre (Voedingscentrum) therefore writes that the blood value is not a good measure for establishing a magnesium deficiency. The measurement is mainly useful with illness, medicine use or an abnormal potassium or calcium. There is no Dutch GP guideline (NHG) that recommends measuring magnesium in people without symptoms.
Who it is for
Useful with prolonged diarrhea or a bowel disease, heavy alcohol use, malnutrition, long-term use of water pills (diuretics) or stomach acid inhibitors (proton pump inhibitors), reduced kidney function and a persistently low potassium or calcium. With tiredness or muscle cramps without these risk factors, the measurement is of little use, because a deficiency is rarely the cause and the blood value does not show a small deficiency well. A vegetarian diet is also not expected to cause a deficiency, because magnesium is abundant in plant-based products.
How often a low magnesium occurs in healthy Dutch people is not known. According to the Netherlands Nutrition Centre (Voedingscentrum), a deficiency does not occur easily, because magnesium is found in many foods, such as whole grain products, vegetables, nuts and dairy products. A low magnesium is mainly seen with bowel or kidney problems, a lot of alcohol and long-term use of water pills or stomach acid inhibitors.
The Netherlands Nutrition Centre (Voedingscentrum), the NVKC and Het Acute Boekje (Netherlands Internists Association)
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Magnesium is part of these test panels. You order online and have your blood drawn at a collection point or collect the sample at home.

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Evidence
This explanation is based on Dutch guidelines and independent information. It is general information, not a diagnosis. Discuss an abnormal result with your GP.
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